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3D cell culture on high porosity and gas-permeable membrane

Hybrid VECELL® H-Plate

Like Preset VECELL, 96-well gas permeable plates wells consists of a hybrid of a high porosity membrane and gas-permeable membrane. Oxygen can be supplied from the bottom of the wells providing a close to in vivo condition for the cell culture. The plates are appropriate for High Content Screening. Black and White color plates are available in the line-up individually and also in packs of 10.

VECELL® Gas Permeable G-Plate

Maintains high CYP activity


High CYP activity of rat hepatocyte (CYP1A1/2 activity) on VECELL® continued for 10 days. Especially on the 10th day, twice the activity of CYP1A1/2 was detected on VECELL® compared to regular plastic plate.


Maintains high albumin secretory function


Change over time of albumin secretory function of rat hepatocyte cultured on VECELL ® H-Plate and on regular plastic plate were measured. The one on VECELL® maintained high albumin secretory function for 9 days. The result indicates that rat hepatocyte demands oxygen, cells on VECELL® kept original shape, a nd were supplied nutrients sufficiently.

Transparency of membrane

Left: Upper side
Right: Bottom side

The membrane turns transparent when it is wet by medium or water. This enable to observe sample cells by microscope.


Free Sample Available!

Product List

Product Name Cat# Quantity Price

VECELL 6 Well H-Plate BK (1)

VCL-V6WHPB-1-EX 1PLATE

¥ 6,000
$ 80
€ 60

VECELL 6 Well H-Plate BK (10)

VCL-V6WHPB-10-EX 1BOX

¥ 60,000
$ 800
€ 600

VECELL 24 Well H-Plate BK (1)

VCL-V24WHPB-1-EX 1PLATE

¥ 6,000
$ 80
€ 60

VECELL 24 Well H-Plate BK (10)

VCL-V24WHPB-10-EX 1BOX

¥ 60,000
$ 800
€ 600

VECELL 6well Plate Trial Set (BK)

VCL-PVHG6WB-3-EX 1*3PLATE

¥ 18,000
$ 240
€ 180

VECELL 24well Plate Trial Set (BK)

VCL-PVHG24WB-3-EX 1*3PLATE

¥ 18,000
$ 240
€ 180

VECELL 96 Well H-Plate BK (1)

VCL-V96WHPB-1-EX 1PLATE

¥ 6,000
$ 80
€ 60

VECELL 96 Well H-Plate BK (10)

VCL-V96WHPB-10-EX 1BOX

¥ 60,000
$ 800
€ 600

VECELL 96 Well H-Plate WT (1)

VCL-V96WHPWT-1-EX 1PLATE

¥ 6,000
$ 80
€ 60

VECELL 96 Well H-Plate WT (10)

VCL-V96WHPWT-10-EX 1BOX

¥ 60,000
$ 800
€ 600

VECELL 384Well H-Plate BK (1)

VCL-V384WHPB-1-EX 1PLATE

¥ 16,000
$ 214
€ 160

References

  • Wenjin Xiao, Makoto Kodama, Kikuo Komori, Yasuyuki Sakai. (2014): Oxygen-permeable membrane-based direct oxygenation remarkably enhances functions and gene expressions of rat hepatocytes in both 3D and sandwich cultures. Biochemical Engineering Journal., Volume 91, 15, Pages 99-109

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.