What is 7-ketocholesterol?
Cholesterol oxidation products, especially 7-Ketocholesterol (7KC), have been the focus of much attention because they are present in human atherosclerotic plaque and display a wide range of atherogenic properties in vitro and to some extant in vivo. This antibody is specific for 7KC. This antibody is useful to detect 7KC in tissue samples. A frozen tissue sample is recommended for immunohistochemistry.
|Antigen:||7KC-modified keyhole-lympet hemocyanine.|
|Form:||Frozen in 10mM PBS containing 0.1 % NaN3 and 0.5% BSA.|
|IgG concentration is 1mg/mL (please take care that only a small volume is in the vial).|
|Specificity:||Specific for 7KC|
|Storage:||Less than -20°C|
|Application:||ImmunohistochemistryIt is recommended that the antibody be tried at 5-10 micro g/mL on frozen tissue.|
|Not applicable to paraffin embedded tissues.|
|Specifity of anti 7-KC antibody.|
|Immunohistochemical detection of 7KC in atherosclerotic aorta.
Noriyuki Shibata et al.
Tokyo Women’s medical University