Podocalyxin is the major sialoprotein of glomerular epithelial cells and contains most of the sialic acid in these cells. Podocalyxin aids in maintaining filtration slit patency and in the maintainance of foot process architecture. Podocalyxin is linked to ezrin and the actin cytoskeleton through interaction with the scaffold protein NHERF2 (Na+/H+-exchanger regulatory factor 2). Podocalyxin has been found in other tissues, though its function in these tissues is unclear.
Western Blotting : 2～5μg / mL
Immunofluorescence : 10μg / mL
Preparation of antibodies and instruction:
|Package Size||25μg (100μL/vial)|
|Rabbit polyclonal antibody 0.25mg/mL
PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]
This antibody was purified from rabbit serum immunized with synthesized partial peptide of Rat Podocalyxin by peptide affinity chromatography.
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