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useful for the research of the function clarification of Aldehyde Oxidase and the influence on the condition.

Anti Rat Aldehyde Oxidase Polyclonal Antibody

Background

Though similar in catalytic function structure and catalytic function, aldehyde oxidase displays higher substrate specificity than xanthine oxidase. Recently, a role for AO in cell differentiation and proliferation involving retinol as AO substrate has been suggested. A role for AO in amyotrophic lateral sclerosis and ischemia/reperfusion failure as also been suggested, due to injury by superoxide produced by AO activity. However, the precise physiological roles of AO remain to be determined.

This antibody shows little cross reaction with xanthine oxidase and has been used to detect AO activity in rat liver. Further, the antibody was found to inhibit AO activity Thus, this antibody will be useful to clarify AO functions in cell and tissue physiology.

Application

western blotting : 0.5〜2μg/mL

Character

Package Size 25μg (100μL / vial)
Format Rabbit polyclonal antibody 0.25mg/mL
Buffer PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]
Storage Store below -20°C
Once thawed, store at 4°C. Repeated freeze-thaw cycles should be avoided.
Purification method This antibody was purified from rabbit serum immunized with Rat Aldehyde Oxidase purified from Rat liver by antigen affinity chromatography.

<Reference>
1. Beedham C. : Drug Metab Rev. 1985;16(1-2):119-56
2. Kisker C. et al. : Annu Rev Biochem. 1997;66:233-67
3. Wright RM. et al. : J Biol Chem. 1999 Feb 5;274(6):3878-86
4. Maia L. et al. : Arch Biochem Biophys. 2002 Apr 1;400(1):48-53
5.Beedham C. ‘Molybdenum Hydroxylases.’ In Enzyme Systems that Metabolise Drugs and Other Xenobiotics, Ioannides C. and John Wiley (ed.), New York, 2002, 147-87

Product List

Product Name Cat# Quantity Price

Anti Aldehyde Oxidase

KAL-KR063 25UG

¥ 49,000
$ 654
€ 490

Anti CaM Kinase II DELTA1/2/3/4

KAL-KY041 200UG

¥ 49,000
$ 654
€ 490

Anti Adenosine Deaminase2

KAL-KR081 25UG

¥ 49,000
$ 654
€ 490

Anti Indoleamine-2,3 dioxygenase / IDO

KAL-KR101 150UG

¥ 49,000
$ 654
€ 490

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.