Mammalian amino acid transport system is consisted of large variety of transporters, with the reflection of amino acid molecule variety, and is classfied into various transport systems by the transportative substrate selectivity and the Na+ dependence with the reflection of amino acid molecule variety. asc-type amino acid transporter 1(Asc-1) is a member of the family of amino acid transporters associated with type II membrane glycoproteins , which requires an additional single membrane spanning protein, 4F2 heavy chain (4F2hc: CD98), for its functional expression. Asc-1 mediates the transport of neutral amino acid, in particular, small neutral amino acids such as Gly, L-ala, L-Ser, L-Thr and L-Cys as substrate in Na+-independent manner. This has been proved to be useful for the immunohistochemistry.
|Package Size||25μg (250μL / Vial)|
|Format||Rabbit polyclonal antibody 0.1 mg/ml|
|Buffer||Block Ace as a stabilizer, containing 0.1%Proclin as bacteriostat|
|Storage||Store below -20°C until needed
Once thawed, store at 4°C. Repeated freeze-thaw cycles should be avoided.
|Purification method||This antidody was purified from rabbit serum immunized with synthesized peptide of mouse Asc1 by peptide affinity chromatography.|
|Working dilution for immunohistochemistry: 30μg/mL, for immunoblotting: 0.1-1μg/mL|
|HGNC Name SLC7A10(Solute Carrier family 7A10)
*HGNC: Human Gene Nomenclature Committee