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powerful tools for biochemical and immunohistochemical analyses of neurodegenerative diseases and for evaluation of cellular or animal models of TDP-43 proteinopathy.

TDP-43 (Native) Rabbit Antibodies

Background

TDP-43, a heterogeneous nuclear ribonucleoprotein, was identified as a component of ubiquitin-positive and tau-negative inclusions observed in cases of frontotemporal lobar degeneration (FTLD-U) and amyotrophic lateral sclerosis (ALS). Immunochemical analyses using antibodies generated against phospho- and non-phosphopeptides of human TDP-43 revealed that abnormally phosphorylated full-length TDP-43 (45 kDa), C-terminal fragments (~25 kDa) and smearing substances are deposited as intracellular inclusions in affected regions of FTLD-U and ALS cases. These antibodies are powerful tools for biochemical and immunohistochemical analyses of neurodegenerative diseases and for evaluation of cellular or animal models of TDP-43 proteinopathy.

Anti TDP-43 N-terminus (3-12) Rabbit Polyclonal Antibody

Antigen : EYIRVTEDENC TDP-43 (3-12)

skein-like inclusion in spinal cord of ALS

1, rat brain extract
2, rat spinal cord extract
3, recombinant human TDP-43

Catalog No.: CAC-TIP-TD-P07

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Anti TDP-43 C-terminus (405-414) Rabbit Polyclonal Antibody

Antigen : CMDSKSSGWGM TDP-43 (405-414)

Nuclei and NCIs in dentate gyrus of FTLD-U

1, rat brain extract
2, rat spinal cord extract
3, recombinant human TDP-43

Catalog No.: CAC-TIP-TD-P09

Products List

Product List

Product Name Cat# Quantity Price

Anti TDP-43 (3-12)

CAC-TIP-TD-P07 100UL

¥ 50,000
$ 667
€ 500

Anti TDP-43 (405-414)

CAC-TIP-TD-P09 100UL

¥ 50,000
$ 667
€ 500

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.