Dppa (developmental pluripotency-associated) 4 is one of genes highly expressed in early embryos and ES cells. DPPA4 associated with transcriptionally active chromatin inhibits differentiation of ES cells into a primitive ectoderm lineage.
|Association of DPPA4 with chromatin in ES cells.|
|(Fig1)Western blot analysis of DPPA4 in chromatin soluble and insoluble fraction.||(Fig.2) Conforcal images of ES cells immunostained with anti-DPPA4 antibodyns (left panel).|
To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.