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useful for the research of the Schwann cell and peripheral myelin.

Anti Schwann Cell/peripheral myelin monoclonal antibody (Schwann/2E)

Specification

Host Mouse
Specificity Reacts to Myelinating Schwann Cells or Myelin Sneath of Human Peripheral Nerve
but not to Oligodendrocytes of Myelin Sneath of Human Central Nerve.
Antigen Human peripheral nerve extract
Clone Schwann/2E
Isotype IgM
Cross reactivity Human, Mouse, Rat

Application

Immunohistochemistry



Result of Immunohistochemistry with Schwann/2E
Schwann/2E positively reacts to Spinal Nerves but negative to Parenchymas (lower light area of the figure)
Sample : Spinal Cord of Human (parafin embedded / fixed with formaldehyde)
Dilution Rate : 1/10000
Staining Methods : Streptoavidin/Biotin





Expansion Graphic of Spinal Nerves stained with Schwann/2E
Schwann Cells and Myelin Sneath are positively stained with Schwann/2E

Product List

Product Name Cat# Quantity Price

Anti Schwann Cell/peripheral myelin

CAC-GU01-M01AS-A 50UL

¥ 30,000
$ 400
€ 300

References
  • Nakazato Y, et al.: Monoclonal antibodies which recognize phosphorylated and nonphosphorylated epitopes of neurofilament protein. Biomed Res 1987, 8:369-376.
  • Arai H, et al.: A novel marker of Schwann cells and myelin of the peripheral nervous system. Pathology Int 1998, 48: 206-214.
  • Jasmin L, et a.: Schwann cells are removed from the spinal cord after effecting recovery from paraplegia. J Neurosci. 2000 20:9215-9223.
  • Jasmin L, et al.: Remyelination within the CNS: do schwann cells pave the way for oligodendrocytes? Neuroscientist. 2002 8:198-203.

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.