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Anti Cdc37 (S. cerevisiae) polyclonal antibody

Background

Cdc37 was initially identified as a cell division cycle control protein of Saccharomyces cerevisiae (1) and was later found to have a much broader role as a molecular chaperone required for folding of protein kinases (2). It forms complex with Hsp90 and a variety of protein kinases and is thought to play a critical role in directing Hsp90 to its target kinases (3). Cdc37 has a molecular weight of 58.4 kD.

Data Link : SGD CDC37/YDR168W

Application

1. Western blotting (2,000 fold dilution).
2. Immunoprecipitation.
3. Indirect immuno-staining
4. Not tested for other applications.


< Western blotting >
lane 1 : x 1000 dilution
lane 2 : x 5000 dilution
Cdc37 protein has a molecular weight of 58.4 kD, but appeared as a 68 kD band in SDS-PAGE.

<Reference>
1. Reed,S.I. “The selection of S. cerevisiae mutants defective in the start event of cell division.”Genetics 95, 561-577 (1980) PMID : 7002718
2. Kimura,Y. et al.“Cdc37 is a molecular chaperone with specific functions in signal transduction.”Genes Dev.11, 1775-1785 (1997) PMID : 9242486
3. Stepanova,L. et al.“Mammalian p50Cdc37 is a protein targeting subunit of Hsp90 that binds and stabilizes Genes Dev.10, 1491-1502 (1996) PMID : 8666233

Product List

Product Name Cat# Quantity Price

Anti Cdc37

BAM-62-302-EX 100UL

¥ 42,100
$ 562
€ 421

Anti Sup35/PSI+

BAM-62-300-EX 100UL

¥ 42,100
$ 562
€ 421

Anti Rnq1

BAM-62-301-EX 100UL

¥ 42,100
$ 562
€ 421