Cut5/Rad4/Dre3 protein is an essential component for DNA replication and also for the damage and checkpoint control which couples S and M phases (1, 2). It interacts with chromatin proteins to form the complex required for the initiation and progression DNA synthesis. It contains 4 BRCT domains and the molecular mass is 74.1 kDa with 648 amino acids.
1) Western blotting (500 fold dilution). Not tested for other applications
Figure Identification of the Cut5/Rad4 protein in the crude extract of S. pombe with this antibody
Lane M : Size markers (kDa)
* Cut5 protein is known to be sensitive to protease digestion in the C-terminal region and the native and the degradation products are observed as described in Ref.2
To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.