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The Rheumera ELISAsystem allows the measurement of anti-type II collagen antibodies in serum from human.

ELISA Assay Kit to measure human antibodies to type II collagen-Reference

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R. B. Clague, K. Morgan, T. I. Reynolds, H. J. Williams. The prevalence of serum IgG antibodies to Type II Collagen in American patients with rheumatoid arthritis. British Journal of Rheumatology, 1994;33:336-338

 

MJ Rowley, B Tait, T Doran, P Emery and IR Mackay. Associations between HLA and antibodies to collagen in rheumatoid arthritis. Annals of the Rheumatic Diseases, 1990, Vol 49, 578-581.

 

Kim W.-U., Yoo W.-H., Won Park, Kang Y.-M., Kim S.-I., Park J.-H., Lee S.-S., Joo Y.-S, Min J.-K., Hong Y.- S., Lee S.-H., Park S.-H., ChoC.-S., Kim H.-Y. IgG antibodies to type II collagen reflect inflammatory activity in patients with rheumatoid arthritis. Journal of Rheumatology, 2000; 27(3):575-581.

 

Rowley MJ, Williamson DJ, Mackay IR Evidence for local synthesis of antibodies to denatured collagen in the synovium in rheumatoid arthritis. Arthritis Rheum. 1987; 30(12):1420-5

 

Terato K., DeArmey D.A., Ye X.J., Griffiths M.M., Cremer M.A. The Mechanism of Autoantibody Formation to Cartilage in Rheumatoid Arthritis: Possible Cross-Reaction of Antibodies to Dietary Collagens with Autologous Type II Collagen. Clin Imm Immunopath, 1996; 79(2):142-154(13)

Terato K, Shimozuru Y, Katayama K, et al. Specificity of antibodies to type II collagen in rheumatoid arthritis. Arthritis Rheum 1990;33:1493-500.

 

Andriopoulos NA, Mestecky J, Miller EJ, Bennett JC. Antibodies to human native denatured collagen in synovial fluid of patients with rheumatoid arthritis. Clin Immunol Immunopathol 1976;6:209-12.

 

Clague RB, Moore LJ. IgG and IgM antibody to native type II collagen in rheumatoid serum and synovial fluid: evidence for the presence of collagen-anticollagen immune complexes in synovial fluid. Arthritis Rheum 1984;27:1370-7.

 

Fujii K, Tsuji M, Kitamura A, Murota K. The diagnostic significance of anti-type II collagen antibody assay in rheumatoid arthritis. Int Orthop 1992;16:272-6.

 

Cook AD, Rowley MJ, Stockman A, Muirden KD, Mackay IR. Specificity of antibodies to type II collagen in early rheumatoid arthritis. J Rheumatol 1994;21:1186-91.

 

Mullazehi M; Mathsson L; Lampa J; Ronnelid J: Surface-bound anti-type II collagen-containing immune complexes induce production of tumor necrosis factor alpha, interleukin-1beta, and interleukin-8 from peripheral blood monocytes via Fc gamma receptor IIA: a potential pathophysiologic mechanism for humoral anti-type II collagen immunity in arthritis. Arthritis Rheum. 2006 Jun;54(6):1759-71

 

Mullazehi M, Mathsson L, Lampa J, Ronnelid J: Anti-collagen type-II antibody levels and induction of proinflammatory cytokines by anti-collagen antibody-containing immune complexes in vitro characterise a distinct rheumatoid arthritis phenotype associated with acute inflammation at the time of disease onset. Ann Rheum Dis. 2007 Apr;66(4):537-41

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