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Anti Human PDCD8 Polyclonal Antibody


- 1.0 - -
IP FCM IF Neutralization
- - 10 -


[WB] human liver tissue lysatelysate

PDCD8 transfected 293T cell lysate

[IF] HeLa cell

< UniPlot Summary>
# Function: Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Extramitochondrial AIF induces nuclear chromatin condensation and large scale DNA fragmentation (in vitro). Binds to DNA in a sequence-independent manner.
# Subcellular location: Mitochondrion intermembrane space. Nucleus. Note: Translocated to the nucleus upon induction of apoptosis.
# Sequence similarities: Belongs to the FAD-dependent oxidoreductase family.


Type Polyclonal Antibody
Immunogen Recombinant protein of full length Human PDCD8
Raised in mouse
Source Mouse Serum
Purification Protein A purified
Cross Reactivity Human
Concentration 1 mg/mL
Contents (Volume) 50 μg
Label Unlabeled
Buffer PBS, pH 7.2
Storage Store at - 20℃ long term, store at 4℃ short term. Avoid repeated freeze-thaw cycles.

1. Susin S.A., et al. "Molecular characterization of mitochondrial apoptosis-inducing factor." Nature 397:441-446(1999)
2. Ota T., et al. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004)
3. Ross M.T., et al. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005))

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To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.