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Anti Mouse Sema4b Monoclonal Antibody (Clone No. TK-2)

Application

WB IHC-P IHC-F IC
1.0 Not Tested Not Tested Not Tested
IP FCM IF Neutralization
5.0 0.05 Not Tested Not Tested

(μg/mL)


[FCM] COS cell expressing mouse Sema4b
The data is provided from Research Institute for Microbial Diseases, Osaka Univ., Japan.

 

<Summary>
#  Function// Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
#  Subunit structure// Interacts with GIPC PDZ domain.
#  Subcellular location// Membrane; Single-pass type I membrane protein.
#  Developmental stage// Expressed from day 10 in the embryo.Low levels found between days 10-12.Expression peaks on day 13 with moderate levels from then until birth.
#  Sequence similarities// Belongs to the semaphorin family.Contains 1 Ig-like C2-type (immunoglobulin-like) domain.

Character

Type Monoclonal Antibody
Immunogen recombinant protein of mouse Sema4B extracellular domain
Raised in GANP mouse
Source Serum-free medium
Purification KAPTIV-M
Cross Reactivity Mouse
Concentration 0.25 mg/mL
Contents(Volume) 25 μg(100 μL/vial)
Label Unlabeled
Buffer PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]
Storage Store at - 20℃ long term, store at 4℃ short term. Avoid repeated freeze-thaw cycles.

<Reference>
1. "cDNA cloning, expression and activity of a second human aflatoxin B1-metabolizing member of the aldo-keto reductase superfamily, AKR7A3." Knight L.P.et al. Carcinogenesis 20:1215-1223(1999) [PubMed: 10383892] [Abstract]. Cited for: NUCLEOTIDE SEQUENCE [MRNA], CHARACTERIZATION, VARIANTS MET-138; ASP-215 AND ALA-323. Tissue: Liver.
2. "Aflatoxin B1 aldehyde reductase (AFAR) genes cluster at 1p35-1p36.1 in a region frequently altered in human tumour cells." Praml C.et al. Oncogene 22:4765-4773(2003) [PubMed: 12879023] [Abstract]. Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY,VARIANTS ASP-215 AND ALA-323.
3. "The DNA sequence and biological annotation of human chromosome 1." Gregory S.G. et al. Nature 441:315-321(2006) [PubMed : 16710414] [Abstract]. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Product List

Product Name Cat# Quantity Price

Anti Sema4B

KAL-KO599 25UG

¥ 55,000
$ 734
€ 550