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Collagen solutions for cell and tissue culturing

AteloCell® References - Atelocollagen, I-PC(1)

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Three-dimensional culture

Research Title Author References PubMed ID
Co-expression of S100A14 and S100A16 correlates with a poor prognosis in human breast cancer and promotes cancer cell invasion. Tanaka M, Ichikawa-Tomikawa N, Shishito N, Nishiura K, Miura T, Hozumi A, Chiba H, Yoshida S, Ohtake T, Sugino T. BMC Cancer. 2015 Feb 13;15:53. 25884418
Recombinant human soluble thrombomodulin attenuates FK506-induced endothelial dysfunction through prevention of Akt inactivation. Eguchi R, Fujimori Y, Okada M, Tamaki H, Wakabayashi I, Ogawa H. Exp Cell Res. 2014 Apr 15;323(1):112-7. 24582967
A human cancer xenograft model utilizing normal pancreatic duct epithelial cells conditionally transformed with defined oncogenes. Inagawa Y, Yamada K, Yugawa T, Ohno S, Hiraoka N, Esaki M, Shibata T, Aoki K, Saya H, Kiyono T. Carcinogenesis. 2014 Aug;35(8):1840-6. 24858378
Differential sensitivity of epithelial cells to extracellular matrix in polarity establishment. Yonemura S. PLoS One. 2014 Nov 13;9(11):e112922. 25393292
FK506 induces endothelial dysfunction through attenuation of Akt and ERK1/2 independently of calcineurin inhibition and the caspase pathway. Eguchi R, Kubo S, Ohta T, Kunimasa K, Okada M, Tamaki H, Kaji K, Wakabayashi I, Fujimori Y, Ogawa H. Cell Signal. 2013 Sep;25(9):1731-8. 23707520
Dynamics of Centrosome Translocation and Microtubule Organization in Neocortical Neurons during Distinct Modes of Polarization. Sakakibara A, Sato T, Ando R, Noguchi N, Masaoka M, Miyata T. Cereb Cortex. 2014 May;24(5):1301-10. 23307632
Nymphaeol-A Isolated from Okinawan Propolis Suppresses Angiogenesis and Induces Caspase-Dependent Apoptosis via Inactivation of Survival Signals. Tsuchiya I, Hosoya T, Ushida M, Kunimasa K, Ohta T, Kumazawa S. Evid Based Complement Alternat Med. 2013;2013:826245. 23710238
Construction of multi-functional extracellular matrix proteins that inhibits migration and tube formation of endothelial cells. Nakamura M, Mie M, Nakamura M, Kobatake E. Biotechnol Lett. 2012 Aug;34(8):1571-7. 22048848
A selective inhibitor of the Rho kinase pathway, Y-27632, and its influence on wound healing in the corneal stroma. Yamamoto M, Quantock AJ, Young RD, Okumura N, Ueno M, Sakamoto Y, Kinoshita S, Koizumi N. Mol Vis. 2012;18:1727-39. 22815626
Features of wound healing shown by fibroblasts obtained from the superficial and deep dermis. Kaminishi-Tanikawa A, Kurita M, Okazaki M, Kawaguchi R, Ihara A, Niikura M, Takushima A, Harii K. J Plast Surg Hand Surg. 2011 Sep;45(4-5):219-25. 22150144
Brazilian Propolis Suppresses Angiogenesis by Inducing Apoptosis in Tube-forming Endothelial Cells through Inactivation of Survival Signal ERK1/2. Kunimasa K, Ahn MR, Kobayashi T, Eguchi R, Kumazawa S, Fujimori Y, Nakano T, Nakayama T, Kaji K, Ohta T. Evid Based Complement Alternat Med. 2011;2011:870753.
Dermal carbonyl modification is related to the yellowish color change of photo-aged Japanese facial skin. Ogura Y, Kuwahara T, Akiyama M, Tajima S, Hattori K, Okamoto K, Okawa S, Yamada Y, Tagami H, Takahashi M, Hirao T. J Dermatol Sci. 2011 Oct;64(1):45-52. 21798719
Calpain is involved in cisplatin-induced endothelial injury in an in vitro three-dimensional blood vessel model. Eguchi R, Fujimori Y, Ohta T, Kunimasa K, Nakano T. Int J Oncol. 2010 Nov;37(5):1289-96. 20878076
Effect of monosaccharides composing glycosaminoglycans on type 2 collagen accumulation in a three-dimensional culture of chondrocytes. Kagita E, Ikeda M, Wakitani S, Takagi M. J Biosci Bioeng. 2010 Jan;109(1):51-4. 20129082
Nobiletin, a citrus polymethoxyflavonoid, suppresses multiple angiogenesis-related endothelial cell functions and angiogenesis in vivo. Kunimasa K, Ikekita M, Sato M, Ohta T, Yamori Y, Ikeda M, Kuranuki S, Oikawa T. Cancer Sci. 2010 Nov;101(11):2462-9. 20670297
Antiangiogenic effects of indole-3-carbinol and 3,3'-diindolylmethane are associated with their differential regulation of ERK1/2 and Akt in tube-forming HUVEC. Kunimasa K, Kobayashi T, Kaji K, Ohta T. J Nutr. 2010 Jan;140(1):1-6. 19889811
Correlation between antiangiogenic activity and antioxidant activity of various components from propolis. Ahn MR, Kunimasa K, Kumazawa S, Nakayama T, Kaji K, Uto Y, Hori H, Nagasawa H, Ohta T. Mol Nutr Food Res. 2009 May;53(5):643-51. 19065585
Possible involvement of caspase-6 and -7 but not caspase-3 in the regulation of hypoxia-induced apoptosis in tube-forming endothelial cells. Eguchi R, Toné S, Suzuki A, Fujimori Y, Nakano T, Kaji K, Ohta T. Exp Cell Res. 2009 Jan 15;315(2):327-35. 19022247
Interaction between PAR-3 and the aPKC-PAR-6 complex is indispensable for apical domain development of epithelial cells. Horikoshi Y, Suzuki A, Yamanaka T, Sasaki K, Mizuno K, Sawada H, Yonemura S, Ohno S. J Cell Sci. 2009 May 15;122(Pt 10):1595-606. 19401335
Intracellular polarity protein PAR-1 regulates extracellular laminin assembly by regulating the dystroglycan complex. Masuda-Hirata M, Suzuki A, Amano Y, Yamashita K, Ide M, Yamanaka T, Sakai M, Imamura M, Ohno S. Genes Cells. 2009 Jul;14(7):835-50. 19549170
Proteomic analysis of hypoxia-induced tube breakdown of an in vitro capillary model composed of HUVECs: potential role of p38-regulated reduction of HSP27. Eguchi R, Naitou H, Kunimasa K, Ayuzawa R, Fujimori Y, Ohashi N, Kaji K, Ohta T. Proteomics. 2008 Jul;8(14):2897-906. 18655027
Differentiation of adipose-derived stromal vascular fraction culture cells into chondrocytes using the method of cell sorting with a mesenchymal stem cell marker. Ishimura D, Yamamoto N, Tajima K, Ohno A, Yamamoto Y, Washimi O, Yamada H. Tohoku J Exp Med. 2008 Oct;216(2):149-56.
Low-intensity pulsed ultrasound activates the phosphatidylinositol 3 kinase/Akt pathway and stimulates the growth of chondrocytes in three-dimensional cultures: a basic science study. Takeuchi R, Ryo A, Komitsu N, Mikuni-Takagaki Y, Fukui A, Takagi Y, Shiraishi T, Morishita S, Yamazaki Y, Kumagai K, Aoki I, Saito T. Arthritis Res Ther. 2008;10(4):R77. 18616830
Suppression of tumor-induced angiogenesis by Brazilian propolis: major component artepillin C inhibits in vitro tube formation and endothelial cell proliferation. Ahn MR, Kunimasa K, Ohta T, Kumazawa S, Kamihira M, Kaji K, Uto Y, Hori H, Nagasawa H, Nakayama T. Cancer Lett. 2007 Jul 18;252(2):235-43. 17343983
Hypoxia induces apoptosis of HUVECs in an in vitro capillary model by activating proapoptotic signal p38 through suppression of ERK1/2. Eguchi R, Suzuki A, Miyakaze S, Kaji K, Ohta T. Cell Signal. 2007 Jun;19(6):1121-31. 17303382
Hypoxia-induced apoptosis and tube breakdown are regulated by p38 MAPK but not by caspase cascade in an in vitro capillary model composed of human endothelial cells. Ohta T, Eguchi R, Suzuki A, Miyakaze S, Ayuzawa R, Kaji K. J Cell Physiol. 2007 Jun;211(3):673-81. 17373651
Atelocollagen for culture of human nucleus pulposus cells forming nucleus pulposus-like tissue in vitro: influence on the proliferation and proteoglycan production of HNPSV-1 cells. Sakai D, Mochida J, Iwashina T, Watanabe T, Suyama K, Ando K, Hotta T. Biomaterials. 2006 Jan;27(3):346-53. 16102816
Effects of low-level hard laser irradiation on mineralization in three-dimensional cultured rat bone marrow cells. Gomi Kazuhiro, Yashima Akihiro, Shirakawa Satoshi, Kanazashi Mikimoto, Sekine Akiko, Kobayashi Kazuyuki, Nagano Takatoshi, Matsui Koutarou, Yamaguchi Hiroyasu, Arai Takashi. J Oral Laser Applications. 2005;5:145-150.
Differentiation of Human Bone Marrow Mesenchymal Stem Cells to Chondrocytes for Construction of Three-dimensional Cartilage Tissue. Matsuda C, Takagi M, Hattori T, Wakitani S, Yoshida T. Cytotechnology. 2005 Jan;47(1-3):11-7. 19003040
Effect of chondroitin sulfate and hyaluronic acid on gene expression in a three-dimensional culture of chondrocytes. Nishimoto S, Takagi M, Wakitani S, Nihira T, Yoshida T. J Biosci Bioeng. 2005 Jul;100(1):123-6. 16233863
Activation of matrix metalloproteinase-2 causes peritoneal injury during peritoneal dialysis in rats. Hirahara I, Ogawa Y, Kusano E, Asano Y. Nephrol Dial Transplant. 2004 Jul;19(7):1732-41. 15128883
Vitronectin or fibronectin is required for corneal fibroblast-seeded collagen gel contraction. Taliana L, Evans MD, Dimitrijevich SD, Steele JG. Invest Ophthalmol Vis Sci. 2000 Jan;41(1):103-9. 10634608
Maintenance of embedded pig pancreatic pseudo-islets in a collagen gel matrix: study of the effect of hydrocortisone, a collagenase inhibitor, and nicotinamide on collagenolysis and the morphogenesis of pancreatic islet-cells in collagen gel matrix. Ohgawara H, Mochizuki N, Taira T, Nishijima S, Iwasaki N, Yui R, Hirata Y, Hayakawa T. In Vitro Cell Dev Biol. 1990 Apr;26(4):348-52. 2160924

Concultivation

Research Title Author References PubMed ID
Hepatocyte growth factor activator inhibitor type 1 maintains the assembly of keratin into desmosomes in keratinocytes by regulating protease-activated receptor 2-dependent p38 signaling. Kawaguchi M, Kanemaru A, Sawaguchi A, Yamamoto K, Baba T, Lin CY, Johnson MD, Fukushima T, Kataoka H. Am J Pathol. 2015 Jun;185(6):1610-23. 25842366
Oncogenic Ras/ERK signaling activates CDCP1 to promote tumor invasion and metastasis. Uekita T, Fujii S, Miyazawa Y, Iwakawa R, Narisawa-Saito M, Nakashima K, Tsuta K, Tsuda H, Kiyono T, Yokota J, Sakai R. Mol Cancer Res. 2014 Oct;12(10):1449-59. 24939643
Characterization of a liver organoid tissue composed of hepatocytes and fibroblasts in dense collagen fibrils. Tamai M, Adachi E, Tagawa YI. Tissue Eng Part A. 2013 Nov;19(21-22):2527-35. 23815236
Enhancement of in vitro human tubulogenesis by endothelial cell-derived factors: implications for in vivo tubular regeneration after injury. Miya M, Maeshima A, Mishima K, Sakurai N, Ikeuchi H, Kuroiwa T, Hiromura K, Yokoo H, Nojima Y. Am J Physiol Renal Physiol. 2011 Aug;301(2):F387-95. 21561997
Development of an endothelial-smooth muscle cell coculture model using phenotype-controlled smooth muscle cells. Sakamoto N, Kiuchi T, Sato M. Ann Biomed Eng. 2011 Nov;39(11):2750-8. 21811870
An in vitro multistep carcinogenesis model for human cervical cancer. Narisawa-Saito M, Yoshimatsu Y, Ohno S, Yugawa T, Egawa N, Fujita M, Hirohashi S, Kiyono T. Cancer Res. 2008 Jul 15;68(14):5699-705. 18632622
Effect of fluid shear stress on migration of vascular smooth muscle cells in cocultured model. Sakamoto N, Ohashi T, Sato M. Ann Biomed Eng. 2006 Mar;34(3):408-15. 16482415
Nitric Oxide Production and Smooth Muscle Cell Phenotype of Endothelial Cell-Smooth Muscle Cell Cocultured Model. Naoya SAKAMOTO, Masaki OI, Toshiro OHASHI and Masaaki SATO. Journal of Biomechanical Science and Engineering, Vol. 1, No. 1 (2006), pp.224-233.
Effect of Shear Stress on Permeability of Vascular Endothelial Monolayer Cocultured with Smooth Muscle Cells. N Sakamoto, T Ohashi, M Sato. JSME international journal. Series C, Mechanical systems, machine elements and manufacturing. 47(4), 992-999, 2004-12-15.

Culture tools coating

Research Title Author References PubMed ID
Engineered bone marrow-derived cell sheets restore structure and function of radiation-injured rat urinary bladders. Imamura T, Ogawa T, Minagawa T, Yokoyama H, Nakazawa M, Nishizawa O, Ishizuka O. Tissue Eng Part A. 2015 May;21(9-10):1600-10. 25669695
Calcineurin B homologous protein 3 negatively regulates cardiomyocyte hypertrophy via inhibition of glycogen synthase kinase 3 phosphorylation. Kobayashi S, Nakamura TY, Wakabayashi S. J Mol Cell Cardiol. 2015 Jul;84:133-42. 25935310
Bovine and porcine fibroblasts can be immortalized with intact karyotype by the expression of mutant cyclin dependent kinase 4, cyclin D, and telomerase. Donai K, Kiyono T, Eitsuka T, Guo Y, Kuroda K, Sone H, Isogai E, Fukuda T. J Biotechnol. 2014 Apr 20;176:50-7. 24589663
Analysis of beat fluctuations and oxygen consumption in cardiomyocytes by scanning electrochemical microscopy. Hirano Y, Kodama M, Shibuya M, Maki Y, Komatsu Y. Anal Biochem. 2014 Feb 15;447:39-42. 24252541
Establishment of cell lines derived from the genus Macaca through controlled expression of cell cycle regulators. Kuroda K, Kiyono T, Eitsuka T, Isogai H, Takahashi K, Donai K, Isogai E, Fukuda T. J Cell Biochem. 2015 Feb;116(2):205-11. 25187009
Cyclic tensile force up-regulates BMP-2 expression through MAP kinase and COX-2/PGE2 signaling pathways in human periodontal ligament cells. Suzuki R, Nemoto E, Shimauchi H. Exp Cell Res. 2014 Apr 15;323(1):232-41. 24561081
Probing the microenvironmental conditions for induction of superficial zone protein expression. Mhanna R, Oztürk E, Schlink P, Zenobi-Wong M. Osteoarthritis Cartilage. 2013 Dec;21(12):1924-32. 23978656
Induction of albumin expression in HepG2 cells using immobilized simplified recombinant fibronectin protein. Nishida Y, Taniguchi A. In Vitro Cell Dev Biol Anim. 2013 Jun;49(6):400-7. ID: 23649815.
Survival of primary human hepatocytes and death of induced pluripotent stem cells in media lacking glucose and arginine. Tomizawa M, Shinozaki F, Sugiyama T, Yamamoto S, Sueishi M, Yoshida T. PLoS One. 2013 Aug 14;8(8):e71897. 23967260
The AP-1 complex regulates intracellular localization of insulin receptor substrate 1, which is required for insulin-like growth factor I-dependent cell proliferation. Yoneyama Y, Matsuo M, Take K, Kabuta T, Chida K, Hakuno F, Takahashi S. Mol Cell Biol. 2013 May;33(10):1991-2003. 23478262
NIH3T3 cells overexpressing CD98 heavy chain resist early G1 arrest and apoptosis induced by serum starvation. Hara K, Ueda S, Ohno Y, Tanaka T, Yagi H, Okazaki S, Kawahara R, Masayuki T, Enomoto T, Hashimoto Y, Masuko K, Masuko T. Cancer Sci. 2012 Aug;103(8):1460-6. 22497681
N-propionyl-4-S-cysteaminylphenol induces apoptosis in B16F1 cells and mediates tumor-specific T-cell immune responses in a mouse melanoma model. Ishii-Osai Y, Yamashita T, Tamura Y, Sato N, Ito A, Honda H, Wakamatsu K, Ito S, Nakayama E, Okura M, Jimbow K. J Dermatol Sci. 2012 Jul;67(1):51-60. 22622238
Activation of macrophage-stimulating protein by human airway trypsin-like protease. Orikawa H, Kawaguchi M, Baba T, Yorita K, Sakoda S, Kataoka H. FEBS Lett. 2012 Feb 3;586(3):217-21. 22245154
Effects of Hypoxia-Inducible Factor-1α Chemical Stabilizer, CoCl(2) and Hypoxia on Gene Expression of CYP3As in Human Fetal Liver Cells. Suzuki E, Matsunaga T, Aonuma A, Sasaki T, Nagata K, Ohmori S. Drug Metab Pharmacokinet. 2012;27(4):398-404. 22277676
Lower expression of HNF4α and PGC1α might impair rifampicin-mediated CYP3A4 induction under conditions where PXR overexpressed in human fetal liver cells. Takezawa T, Matsunaga T, Aikawa K, Nakamura K, Ohmori S. Drug Metab Pharmacokinet. 2012;27(4):430-8. 22333269
Cyclic stretch induces upregulation of endothelin-1 with keratinocytes in vitro: possible role in mechanical stress-induced hyperpigmentation. Kurita M, Okazaki M, Fujino T, Takushima A, Harii K. Biochem Biophys Res Commun. 2011 May 27;409(1):103-7. 21557930
The TRPV4 channel is a novel regulator of intracellular Ca2+ in human esophageal epithelial cells. Ueda T, Shikano M, Kamiya T, Joh T, Ugawa S. Am J Physiol Gastrointest Liver Physiol. 2011 Jul;301(1):G138-47. 21493730
Expansion and characterization of adipose tissue-derived stromal cells cultured with low serum medium. Hattori H, Nogami Y, Tanaka T, Amano Y, Fukuda K, Kishimoto S, Kanatani Y, Nakamura S, Takase B, Ishihara M. J Biomed Mater Res B Appl Biomater. 2008 Oct;87(1):229-36. 18496860
Nuclear deformation and expression change of cartilaginous genes during in vitro expansion of chondrocytes. Hoshiba T, Yamada T, Lu H, Kawazoe N, Tateishi T, Chen G. Biochem Biophys Res Commun. 2008 Oct 3;374(4):688-92. 18675249
Visible light regulates neurite outgrowth of nerve cells. Higuchi A, Watanabe T, Noguchi Y, Chang Y, Chen WY, Matsuoka Y. Cytotechnology. 2007 Jul;54(3):181-8. 18832797
Expression of CCN1 (CYR61) in developing, normal, and diseased human kidney. Sawai K, Mukoyama M, Mori K, Kasahara M, Koshikawa M, Yokoi H, Yoshioka T, Ogawa Y, Sugawara A, Nishiyama H, Yamada S, Kuwahara T, Saleem MA, Shiota K, Ogawa O, Miyazato M, Kangawa K, Nakao K. Am J Physiol Renal Physiol. 2007 Oct;293(4):F1363-72. 17699553
Altered gene expression related to glomerulogenesis and podocyte structure in early diabetic nephropathy of db/db mice and its restoration by pioglitazone. Makino H, Miyamoto Y, Sawai K, Mori K, Mukoyama M, Nakao K, Yoshimasa Y, Suga S. Diabetes. 2006 Oct;55(10):2747-56. 17003339
Regulation of neurite outgrowth by intermittent irradiation of visible light. Higuchi A, Watanabe T, Matsubara Y, Matsuoka Y, Hayashi S. J Phys Chem B. 2005 Jun 2;109(21):11033-6. 16852344
Platelet-rich plasma provides nucleus for mineralization in cultures of partially differentiated periodontal ligament cells. Kawase T, Okuda K, Saito Y, Amizuka N, Suzuki H, Yoshie H. In Vitro Cell Dev Biol Anim. 2005 May-Jun;41(5-6):171-6. 16153151
Visible light is able to regulate neurite outgrowth. Higuchi A, Kitamura H, Shishimine K, Konishi S, Yoon BO, Hara M. J Biomater Sci Polym Ed. 2003;14(12):1377-88. 14870941
A simple electroporation method for the introduction of plasmids into cells cultured on coverslips for histochemical examination. TAKATA Kuniaki ; TAKAHASHI Yukiko ; MATSUZAKI Toshiyuki ; TAJIKA Yuki ; SUZUKI Takeshi ; AOKI Takeo ; HAGIWARA Haruo. Act Histochem Cytochem,2003; 36 (4):317-23.
Synergistic effect of BMP-2 and ascorbate on the phenotypic expression of osteoblastic MC3T3-E1 cells. Torii Y, Hitomi K, Tsukagoshi N. Mol Cell Biochem. 1996 Dec 6;165(1):25-9. 8974078