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Extracellular Vesicles Research

Antibodies for Exosome; Anti CD9, CD63, CD81 Antibodies

Background

Exosome are cell-derived vesicles formed by a lipid bilayer membrane, and its diameter is 40-100 nm. Exosomes are observed in body fluid, such as saliva, blood, urine, amniotic fluid, malignant ascites, and are secreted from cultured cells. Recently, it has been shown that exosomes include various proteins and RNAs, which have a possibility to function in intercellular signal transduction. These products are the antibodies which can specifically detect CD9, CD63 and CD81 known as exosome markers. These antibodies are suitable for isolation of exosome by immunoprecipitation.

Feature and Advantages

-High specificity for exosome membrane proteins CD9, CD63, CD81

-100% of exosomes in a 150 ul sample can be isolated by using only 1 ug of antibody
Supported samples:
CD9…serum
CD63…serum, culture supernatant
CD81…serum, culture supernatant

-Useful for analyses of exosome surface antigen proteins, endogenous RNA (miRNA) and proteins

Application Examples

1) IP-WB of exosome in serum sample using Anti-CD9 antibody (12A12)

IP-WB of exosome in serum sample using Anti-CD9 antibody (12A12)

2) IP-WB of exosome in serum sample using Anti-CD63 antibody (8A12)

IP-WB of exosome in serum sample using Anti-CD63 antibody (8A12)

3) IP-WB of exosome in serum sample using Anti-CD81 antibody (12C4)

IP-WB of exosome in serum sample using Anti-CD81 antibody (12C4)

Product List

Product Name Cat# Quantity Price

Anti CD9

CAC-SHI-EXO-M01 50UL

¥ 35,000
$ 467
€ 350

Anti CD9

CAC-SHI-EXO-M01 100UL

¥ 65,000
$ 867
€ 650

Anti CD63

CAC-SHI-EXO-M02 50UL

¥ 35,000
$ 467
€ 350

Anti CD63

CAC-SHI-EXO-M02 100UL

¥ 65,000
$ 867
€ 650

Anti CD81

CAC-SHI-EXO-M03 50UL

¥ 35,000
$ 467
€ 350

Anti CD81

CAC-SHI-EXO-M03 100UL

¥ 65,000
$ 867
€ 650

ExoTrap Exosome Isolation Spin Column Kit for Protein Research

CSR-SHI-EXO-K010 10PREP.

¥ 57,000
$ 760
€ 570

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.