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Anti Nε-(carboxyethyl) lysine (CEL) monoclonal antibody

Background

Nε-(carboxyethyl) lysine (CEL) is generated from protein modification by methylglyoxal (MG), which is enzymatically derived from the Embden-Meyerhof and polyol pathways, through the degradation of glyceraldehyde-3-phosphate (G3P) (Phillips and Thornalley, 1993). Mclellan et al.(McLellan et al., 1994) demonstrated that plasma MG Concentrations in insulin-dependent diabetic patients were 7-times higher than those of healthy individuals.

<CEL production pathway>
CAC_JWUM02_2.gif

Application

Western blotting, 1/200 to 1/400
Immunohistochemistry, 1/100 to 1/200
ELISA, 1/200 to 1/400

References
Nagai R,et al., J Immunol Methods. 2008 Mar 20;332(1-2):112-20. doi: 10.1016/j.jim.2007.12.020. Epub 2008 Jan 28. PMID: 18242632

Product List

Product Name Cat# Quantity Price

Anti N(EPSILON)-(carboxyethyl) lysine (CEL)

CAC-AGE-M02 100UL

¥ 50,000
$ 667
€ 500

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.