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Antibody for Histone H3.1/H3.2

Anti Histone H3.1/H3.2 Monoclonal Antibody (6G3C7)

Background

Nucleosomes are composed of four different histone proteins, designated H3, H4, H2A, and H2B. Histone H3 has two main variants, H3.1 and H3.3, which show different genomic localization patterns in eukaryotes. Deposition of Histone H3.1 is coupled to DNA synthesis during DNA replication and possibly DNA repair.

Application

・ Western blotting: 1/10000

Other applications have not been tested.
Optimal dilutions/concentrations should be determined by the end user.

CAC_CE039A_2
Western blot analysis of recombinant protein and mammalian cell extracts using Histone H3.1/H3.2 antibody, 6G3C7.

The composition of Histone H3 variants peptides and the reactivity using Histone H3.1/H3.2 antibody, 6G3C7.

CAC_CE039A_1 H3.1 peptide
H3.3 peptide
79 KTDLRFQSSAVMALQEASEA 97
79 KTDLRFQSAAIGALQEASEA 97

Product List

Product Name Cat# Quantity Price

Anti Histone H3.1/H3.2

CAC-CE-039A 100UL

¥ 58,000
$ 774
€ 580

References

1) Hake and Allis, (2006) PNAS, 103, 6428-6435
2) Harada et al., (2012) EMBO J. doi: 10.1038/emboj.2012.136.

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.