Recently, it could be shown that the induction of CK 8/18 expression in non-malignant buccal mucosa cells resulted in a significant change of phenotypic characteristics after CK 8/18 transfection. These changes include an increased cellular motility, which might give first hints for an increased tumor aggressiveness and poor patient prognosis.
Western blotting, 1/1,000 to 1/5,000
Immunocytochemistry, 1/100 to 1/500
Immunohistochemistry, 1/100 to 1/500
Fig.1 Immunocytochemistry/ Immunofluorescence -
Cytokeratin-18(CK18) antibody (D2C7)
Fig.2 Western blot - Cytokeratin-18(CK18) antibody (D2C7)
1.HeLa, 2.COS1, 3.rat liver, 4.mouse liver total extracts
Optimal dilutions/concentrations should be determined by the end user.
Anti Cytokeratin18 (CK18)
1. Linder et al.,(2004) Determining tumor apoptosis and necrosis in patient serum using
cytokeratin 18 as a biomarker. Cancer Lett.,214,1-9.
To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.