Exportin-5 (XPO5) mediates the nuclear export of proteins bearing a double-stranded RNA binding domain (dsRBD) and double-stranded RNAs (cargos). XPO5 in the nucleus binds cooperatively to the RNA and to the GTPase Ran in its active GTP-bound form.
Western blotting, 1/1000 to 1/5000
Immunocytochemistry, 1/100 to 1/500
Fig.1 Immunocytochemistry/ Immunofluorescence - Exportin-5 antibody (1D11)
Fig.2 Western blot - Exportin-5 antibody (1D11) HeLa cell nuclear extracts Optimal dilutions/concentrations should be determined by the end user.
1. Katahira and Yoneda, (2011) Traffic, 12, 1468-1474.
To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.