Oct4/Pou5f1 is a member of POU transcription factor family, which possess POU domain. This transcription factor forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Oct4/Pou5f1 is critical for early embryogenesis and for embryonic stem cell pluripotency.
Western blotting : Recommended dilutions 1/1000 to 1/5000
Immunocytochemistry : Recommended dilutions 1/100 to 1/500
< Immunocytochemistry / Immunofluorescence >
< Western blotting >
< Reference >
1) Sterneckert, J. et al. (2011) Oct4 and More: The Reprogramming Expressway. Stem Cells. Oct 18. [Epub ahead of print]
To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.