Gonadotropin Releasing Hormone (GnRH), also know as Luteinizing-hormone-releasing-hormone (LHRH) and luliberin, is a tropic peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and Luteinizing Hormone (LH) from the anterior pituitary. GnRH is synthesized and released from neurons within the hypothalamus. The peptide belongs to gonadotropin-releasing hormone family
Recommended Antibody Dilutions
Radioimmunoassay : 1/100,000 - 1/400,000
Western blotting : 1/5,000 - 1/20,000
Neutrization : n/d
< Radioimmunoassay >
1) Miyamoto K, Hasegawa Y, Nomura M, lgarashi M, Kangawa K & Matsuo H (1984)Identification of the second gonadotropin-releasing hormone in chicken hypothalamus:Evidence that gonadotropin secretion is probably controlled by two distinct gonadotropin-releasing hormones in avian species.Proc Natl Acad Sci USA 81: 3874-3878
2) 2.Amano M, Oka Y, Aida K, Okumoto N, Kawashima S & Hasegawa Y (1991) Immunocytochemical demonstration of salmon GnRH and chicken GnRH-II in the brain of masu salmon, Oncorhynchus masou. J Comp Neurol 314: 587-597.
3) Kobayashi M, Amano M, Kim MH, Furukawa K, Hasegawa Y & Aida K (1994) Gonadotropin releasing hormones of terminal nerve original are not essential to ovarian development and ovulation in goldfish. Gen Com Endocrinol 95: 192-200
4) ISHIZAKI M, IIGO M, YAMAMOTO N, and OKA Y (2004) Different Modes of Gonadotropin-Releasing Hormone (GnRH) Release from Multiple GnRH Systems as Revealed by Radioimmunoassay Using Brain Slices of a Teleost, the Dwarf Gourami (Colisa lalia) Endocrinology 145: 20922103
To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.