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Powerful tools in studying DNA damage and its biological effects

Antibodies against Nucleotide excision repair (NER)

Anti XPA monoclonal antibody [Clone : A-2]
Anti XPF monoclonal antibody [Clone : 19-16]
Anti XPG monoclonal antibody [Clone : G-26]
Anti ERCC1 monoclonal antibody [Clone : E1-44]

 

Monoclonal Antibodies against DNA Damage

 

Background

Nucleotide excision repair (NER) is a major repair system for removing a variety of DNA lesions including UV-induced cyclobutane pyrimidine dimer and (6-4) photoproduct as well as chemical-induced bulky base adducts. Defects in the NER system give rise to xeroderma pigmentosum (XP), an autosomal recessive disease characterized by a predisposition to skin cancer and in some cases neurological abnormalities. The early process of human NER, from damage recognition to dual incision (removal of damage-containing oligonucleotides), is accomplished by six core NER factors, XPC-RAD23B, TFIIH, XPA, RPA, ERCC1-XPF and XPG in vitro.

Application

<Western blotting>

Product List

Product Name Cat# Quantity Price

Anti XPA

CAC-KUP-TM-M01 100UL

¥ 50,000
$ 667
€ 500

Anti XPF

CAC-KUP-TM-M02 100UL

¥ 50,000
$ 667
€ 500

Anti XPG

CAC-KUP-TM-M03 100UL

¥ 50,000
$ 667
€ 500

Anti ERCC1

CAC-KUP-TM-M04 100UL

¥ 50,000
$ 667
€ 500

Antibodies and Kits to DNA Replication, Recombination & Repair

Oxidized DNA damage markers

DNA Damage products