PRODUCT CATEGORY

PRODUCT SEARCH

NEWSLETTER

Register now!Newsletter subscription

  • CATALOG PDF Download
  • BROCHURES PDF Download

Anti-Rad18 (human) Polyclonal Antibody

Background

The Rad6-Rad18 pair of genes plays a critical role in post-replication repair of damaged DNA. Rad6 protein functions as an E2 enzyme and Rad18 as an ubiquitine ligase (E3) which ubiquitinates PCNA. Rad18 recruits translesion DNA polymerases to damaged DNA.

Application

• WB (1000 fold dilution)
• IF
• IP

Optimal dilutions/concentrations should be determined by the end user.

BAM_70023EX_1
Indirect immunofluorescence staining of Rad18 protein in GM637 cells. Rad18 protein is stained as yellow dots in nuclei.
BAM_70023EX_2
Identification of Rad18 protein in crude extract of A549 cells by Western blotting.
The lower thick band is native Rad18 and the upper thin band is mono-ubiquitinated Rad18 protein

Product List

Product Name Cat# Quantity Price

Anti Rad18

BAM-70-023-EX 100UG

¥ 34,500
$ 460
€ 345

References

・ Miyase S et al J Biol Chem 280: 515-524 (2005)
・ Tateishi S et al PNAS 97: 7927-7932 (2000)
・ Watanabe K et al EMBO J 23: 3886-3896 (2004)

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.