Register now!Newsletter subscription

  • CATALOG PDF Download
  • BROCHURES PDF Download

Anti RagA polyclonal antibody


RagA (313 aa, 36.6 kDa) is the human homologue of Gtr1 identified in yeast and classified as the Ras-like small G protein family. In cytoplasm, GTP-bound RagA usually forms a heterodimer with RagD, interacts with Nop132 to be transported to the nucleous. GTP of RagA is hydrolyzed to GDP by RCC, guanine nucleotide exchange factor for RanGTPase bound to chromatin. RagA-RCC signal pathway has a crucial role in cell growth and differentiation. RagA is also well known to be involved in mTOR signaling via binding with raptor, a component of mTORC1 complex, in an amino acid sensitive manner.

Data Link  UniProtKB/Swiss-Prot : Q7L523


1) Western blotting ( 1,000 - 2,000 folds dilution)

Western blot analysis of RagA protein in the whole cell extracts (HeLa cell lysate, 10mg). Anti-RagA antiserum was used at 1,000 dilution.

Product List

Product Name Cat# Quantity Price


BAM-71-020-EX 100UL

¥ 33,000
$ 440
€ 330

1. Sekiguchi T et al “ A nobel human nucleolar protein Nop132, binds to the G proteins, RRAG A/C/D" J. Biol. Chem. 279,: 8343-8350 (2004) PMID : 14660641
2. Yasemin S et al “The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1” Science. 320(5882): 1496-1501 (2008) PMID: 18497260

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.