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Anti Hepatitis C virus (HCV) NS5a protein Monoclonal antibody

Background

 Hepatitis C virus (HCV) is a small (55-65 nm in size), enveloped, positive sense single-stranded RNA virus in the family Flaviviridae and the principal cause of parenteral non-A, non-B hepatitis. The virus genome consists of a single open reading frame of approximately 9,400 bases which encodes a single polyprotein of about 3,010 amino acids (1, 2, 3). The polyprotein is processed by host cell and viral proteases into four structural proteins (core, envelope1 and 2, and p7) and six non-structural proteins (NS2, 3, 4a, 4b, 5a, and 5b) necessary for viral replication. The primary function of NS5a is not known, but from the comparative studies with other viruses it is predicted to play a role in RNA replication.

Data Link : Swiss-Prot HCV protein

Application

1. Western blotting               
2. Immunofluorescence staining
Other applications have not been tested.

   
References

1. Choo, Q-L. et al. (1989) “Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 244, 359-362 PMID: 2523562
2. Kato,N. et al. (1990) “Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis.” Proc. Natl. Acad. Sci. USA 87, 9524-9528 PMID: 2175903
3. Takamizawa, A. et al. (1991) “Structure and organization of the hepatitis C virus genome isolated from human carriers.” J.Virol.65, 1105-1113 PMID: 1847440
4. Manabe,S. et al. (1994) “Production of nonstructural proteins of hepatitis C virus requires a putative viral protease encoded by N3.” Virology 198, 636-644 PMID: 8291245

Product List

Product Name Cat# Quantity Price

Anti HCV NS5a protein

BAM-65-062-EX 100UG

¥ 31,500
$ 420
€ 315

Anti HCV NS5a protein

BAM-65-063-EX 50UG

¥ 31,500
$ 420
€ 315

Anti HCV NS5a protein

BAM-65-064-EX 50UG

¥ 31,500
$ 420
€ 315

Anti HCV Core protein

BAM-65-052-EX 100UG

¥ 34,900
$ 466
€ 349

Anti HCV Core protein

BAM-65-053-EX 50UG

¥ 31,500
$ 420
€ 315

Anti HCV Core protein

BAM-65-054-EX 50UG

¥ 31,500
$ 420
€ 315

Anti HCV NS4a protein

BAM-65-057-EX 100UG

¥ 31,500
$ 420
€ 315

Anti HCV NS4a protein

BAM-65-058-EX 50UG

¥ 31,000
$ 414
€ 310

Anti HCV NS4a protein

BAM-65-059-EX 50UG

¥ 31,000
$ 414
€ 310

Anti HCV NS5b protein

BAM-65-067-EX 100UG

¥ 31,500
$ 420
€ 315

Anti HCV NS5b protein

BAM-65-068-EX 50UG

¥ 31,500
$ 420
€ 315

Anti HCV NS5b protein

BAM-65-069-EX 50UG

¥ 31,000
$ 414
€ 310

1. Choo, Q-L. et al. (1989) “Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 244, 359-362 PMID: 2523562 2. Kato,N. et al. (1990) “Molecular cloning of the human hepatitis C virus genome from Japanese patie