For Research Use Only
Pancreas duodenum homeobox 1 (PDX1) is a transcription factor encoded by homeodomein gene. This protein promotes the transcription of the pancreatic genes such as insulin and somatostatin, so that it is indispensable for keeping normal function of pancreatic beta cell. As it is involved in secretion of insulin, PDX1 becomes therapeutic target against pancreatic diseases such as diabetes and cancer.
This antibody specifically reacts with PDX1 in mouse pancreas and foregut (primordial pancreas). This antibody is useful for immunohistochemistry and could become good research tool for studying pancreatic function, embryology, and diabetes.
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