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Anti Mouse Trpm7 Polyclonal Antibody

Background

Function : Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).
Tissue specificity : Found to be expressed in brain and skeletal muscle, with stronger signals in kidney, heart, liver and spleen.
Sequence similarities : In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily. In the N-terminal section; belongs to the transient receptor family. LTrpC subfamily. Contains 1 alpha-type protein kinase domain.

Application

ELISA WB IHC ICC
1.0 μg/mL Not tested Not tested Not tested
IP FCM IF Neutralization
Not tested Not tested Not tested Not tested

Character

Type Polyclonal Antibody
Immunogen Partial peptide of Mouse Trpm7 C-terminal region
Raised in Rabbit
Source Rabbit Serum
Purification notes Antigen Affinity
Cross Reactivity Human
Concentration 0.25 mg/mL
Contents (Volume) 25 μg (100 μL/vial)
Label Unlabeled
Buffer PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]
Storage Store below -20 °C. Once thawed, store at 4 °C. Repeated freeze-thaw cycles should be avoided.

Product List

Product Name Cat# Quantity Price

Anti Trpm7

KAL-KO464 25UG

¥ 49,000
$ 654
€ 490

Anti TRPV1 / VR-1

KAL-KM018 5UG

¥ 49,000
$ 654
€ 490

Anti TRPV1 / VR-1, phospho Ser800

KAL-KM112 25UG

¥ 49,000
$ 654
€ 490

Anti TRPV2 / VRL-1

KAL-KM019 5UG

¥ 49,000
$ 654
€ 490

Anti TRPA 1

KAL-KM120 50UG

¥ 49,000
$ 654
€ 490

Anti TRPV 4

KAL-KM119 25UG

¥ 49,000
$ 654
€ 490

Anti Rim1

KAL-KO454 25UG

¥ 49,000
$ 654
€ 490

Anti Cacnb4

KAL-KO455 25UG

¥ 49,000
$ 654
€ 490

Anti Trpc3

KAL-KO457 25UG

¥ 49,000
$ 654
€ 490

Anti Trpc5

KAL-KO459 25UG

¥ 49,000
$ 654
€ 490

Anti Trpc6

KAL-KO460 25UG

¥ 49,000
$ 654
€ 490

Anti Trpm1

KAL-KO461 25UG

¥ 49,000
$ 654
€ 490

Anti Trpm2

KAL-KO462 25UG

¥ 49,000
$ 654
€ 490

Anti Trpm2

KAL-KO463 25UG

¥ 49,000
$ 654
€ 490

References
  • Numata T, et al. TRPM7 is a stretch- and swelling-activated cation channel involved in volume regulation in human epithelial cells. Am J Physiol Cell Physiol. 2007 Jan;292(1):C460-7. *Application Reference
  • Hanano T, et al. Involvement of TRPM7 in cell growth as a spontaneously activated Ca2+ entry pathway in human retinoblastoma cells. J Pharmacol Sci. 2004 Aug;95(4):403-19. *Application Reference