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Anti Mouse Trpc6 Polyclonal Antibody

Background

Function : Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.
Tissue specificity : Lung and brain. Post-translational modification: N-glycosylated.
Sequence similarities : Belongs to the transient receptor family. STrpC subfamily. Contains 3 ANK repeats.

Application

ELISA WB IHC ICC
1.0 μg/mL Not tested 5.0-10 μg/mL 1.0-5.0 μg/mL
IP FCM IF Neutralization
Not tested Not tested Not tested Not tested

Character

Type Polyclonal Antibody
Immunogen Partial peptide of Mouse Trpc6 C-terminal
Raised in Rabbit
Source Rabbit Serum
Purification notes Antigen Affinity
Cross Reactivity  
Concentration 0.25 mg / mL
Contents (Volume) 25 μg (100 μL / vial)
Label Unlabeled
Buffer PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]
Storage Store below -20 °C. Once thawed, store at 4 °C. Repeated freeze-thaw cycles should be avoided.

<Reference>
1. Inoue R, et al. The transient receptor potential protein homologue TRP6 is the essential component of vascular alpha(1)-adrenoceptor-activated Ca(2+)-permeable cation channel. Circ Res. 2001 Feb 16;88(3):325-32. *Application Reference.

Product List

Product Name Cat# Quantity Price

Anti Trpc6

KAL-KO460 25UG

¥ 49,000
$ 654
€ 490

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.