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Anti Mouse Trpc3 Polyclonal Antibody

Background

Function : Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol-1,4,5-triphosphate receptors (ITPR) with bound IP3. May also be activated by internal calcium store depletion.
Tissue specificity : Abundantly expressed in brain. Concentrated in cerebellar Purkinje cells and sparsely localized in cerebellar granule lyer, pontine nuclei and thalamus. Lower levels detected in other tissues.
Sequence similarities : Belongs to the transient receptor family. STrpC subfamily. Contains 5 ANK repeats.

Application

Catalog number : KAL-KO456
ELISA WB IHC ICC
1.0 μg/mL 1.0-5.0 μg/mL Not tested Not tested
IP FCM IF Neutralization
Not tested Not tested Not tested Not tested
Catalog number : KAL-KO457
ELISA WB IHC ICC
1.0 μg/mL Not tested Not tested Not tested
IP FCM IF Neutralization
Not tested Not tested Not tested Not tested

Character

Type Polyclonal Antibody
Immunogen Partial peptide of Mouse Trpc3 C-terminal
Raised in Rabbit
Source Rabbit Serum
Purification notes Antigen Affinity
Cross Reactivity  
Concentration 0.25 mg/mL
Contents (Volume) 25 μg (100 μL/vial)
Label Unlabeled
Buffer PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]
Storage Store below -20 °C. Once thawed, store at 4 °C. Repeated freeze-thaw cycles should be avoided.

<Reference>
1. Mori Y, et al. Differential distribution of TRP Ca2+ channel isoforms in mouse brain. Neuroreport. 1998 Feb 16;9(3):507-15.

Product List

Product Name Cat# Quantity Price

Anti Trpc3

KAL-KO456 25UG

¥ 49,000
$ 654
€ 490

Anti Trpc3

KAL-KO457 25UG

¥ 49,000
$ 654
€ 490

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.