Addicsin(also named GTRAP3-18) was identified as novel gene upregulated in mouse amygdala with morphine torelant and dependent state. (Ref.1,2) On the other hand, GTRAP3-18 is newly identified protein of its rat homolog which encodes a putative modulator of neural glutamate-transporter EAAC1.
Addicsin is involved in regulating glutamate content in brain and it might be a key molecule of neuroplasticity and the neuropathology of addiction of drug, dementia, epilepsy, etc. This antibody was established from the purified serum immunized with partial peptide of mouse addicsin.
This antibody is useful for western blotting and immunohistochemistry.
Sample:mouse brain (ddY strain、male、6 weeks) homogenate
Preparation of antibodies and instruction
1. Ikemoto MJ, et al. ; Neuroreport 16, 2079-2084, 2002.
2. Ikemoto M, et al. ; Nature Medicine 6, 910-915, 2000.
3. Lin CI, et al. ; Nature 410, 84-88, 2001.
|Package Size||25μg (100μL/vial)|
|Rabbit polyclonal antibody 0.25mg/mL
Block Ace as a stabilizer, containing 0.1% Proclin as a bacteriostat
This antibody was purified from rabbit serum by affinity chromatography.
|Working dilution||For western blotting ; 1〜5 μg/mL
For Immunohistochemistry ; 0.5 〜2 μg/mL