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Anti α-Synuclein Antibodies

Go to Antibodies for Neurodegenerative Disease Research page

Alpha-Synuclein, a 140-amino acid protein abundantly expressed in presynaptic terminals, is known as a component of intraneuronal or glial inclusions observed in cases of Parkinson's disease (PD), Dementia with Lewy bodies (DLB) and Multiple system atrophy (MSA). Alpha-Synuclein is a natively unfolded protein, however, fibrillization or conformational change of Alpha-synuclein is central in the pathogenesis of Alpha-synucleinopathies. The amino-terminal region of Alpha-synuclein consists of seven imperfect repeats, each 11 amino acids in length, with the consensus sequence KTKEGV. The repeats partially overlap with a hydrophobic region (amino acids 61-95). The carboxy-terminal region (amino acids 96-140) is negatively charged. These antibodies are powerful tools for biochemical and IHC analyses of neurodegenerative diseases and for evaluation of conformational changes of Alpha-synuclein.

Product List

Product Name Cat# Quantity Price

Anti (ALPHA) Synuclein (1-10)

CAC-TIP-SN-P01 50UL

¥ 32,000
$ 534
€ 400

Anti (ALPHA) Synuclein (11-20)

CAC-TIP-SN-P02 50UL

¥ 32,000
$ 534
€ 400

Anti (ALPHA) Synuclein (21-30)

CAC-TIP-SN-P03 50UL

¥ 32,000
$ 534
€ 400

Anti (ALPHA) Synuclein (31-40)

CAC-TIP-SN-P04 50UL

¥ 32,000
$ 534
€ 400

Anti (ALPHA) Synuclein (41-50)

CAC-TIP-SN-P05 50UL

¥ 32,000
$ 534
€ 400

Anti (ALPHA) Synuclein (51-60)

CAC-TIP-SN-P06 50UL

¥ 32,000
$ 534
€ 400

Anti (ALPHA) Synuclein (61-70)

CAC-TIP-SN-P07 50UL

¥ 32,000
$ 534
€ 400

Anti (ALPHA) Synuclein (75-91)

CAC-TIP-SN-P08 50UL

¥ 32,000
$ 534
€ 400

Anti (ALPHA) Synuclein (131-140)

CAC-TIP-SN-P09 50UL

¥ 32,000
$ 534
€ 400

Anti (ALPHA) Synuclein (9 antibodies set)

CAC-TIP-SN-SET 9*10UL

¥ 72,000
$ 1200
€ 900

References
  • Masami Masuda, et al. Inhibition of a-synuclein fibril assembly by small molecules: A FEBS Letters (2009) 583, 787-791. PMID 19183551
  • Motokuni Yonetani, et al. Conversion of wild-type alpha-synuclein into mutant-type fib A30P mutant. Journal of Biological Chemistry (2009) 284, 7940-7950. PMID 19164293

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.