We provide service of macromolecules imaging including proteins in various states at the single molecule-level by combining conventional electron tomography and a specifically designed 3D reconstruction program known as COMET. The current resolution of a 3D image produced by this technique is approximately 1.5nm and the resolution is steadily improving. For decades, pharmaceutical companies have studied the structure of proteins on the surface of human cells to develop drugs that latch onto the proteins and block the entry of a virus or bacteria. The new technology also allows visualization of protein complexes and their dynamics, serving as an alternative solution to the study of biological samples that are difficult or impossible to crystallize. The ultimate goal of imaging protein structures is to provide data for new drug design. By utilizing data obtained by the new technology at various stages of the drug development, pharmaceutical companies will be able to analyze drug candidates efficiently and effectively.