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Limited-Time Saving 20% OFF on High Sensitivity ELISA KIT for measuring UV-induced DNA damage [Campaign Code: 1065]


This Offer starts from December 1st, 2016 to February 28th, 2017
Except for USA customers. Customers in the USA, please contact Cosmo Bio USA, Inc


The major types of DNA damage induced by solar UV radiation are cyclobutane pyrimidine dimers (CPDs), and (6-4) photoproducts (6-4PPs), which are formed between adjacent pyrimidine nucleotides on the same DNA strand. These helix-distorting DNA lesions are repaired exclusively by a nucleotide excision repair system in humans.

Our High Sensitivity Cyclobutane Pyrimidine Dimers (CPDs) ELISA Kit is the only commercially available ELISA utilizing anti-CPD clone TDM-2 and has been optimized for high sensitivity detection of CPDs in DNA purified from cultured cells or from skin epidermis. Another Kit; High Sensitivity (6-4)photoproducts (6-4PPs) ELISA Kit is the only commercially available ELISA utilizing anti-6-4PPs clone 64M-2 and has been optimized for
high sensitivity detection of 6-4PPs in DNA purified from cultured cells or from skin epidermis.

This ELISA detects CPDs or 6-4PPs from dipyrimidines in all DNA sequence contexts (i.e., TT, TC, CT and CC). Thus, the availability and convenience of this ELISA Kit will contribute to further understanding molecular mechanisms involved in cellular responses to UV radiation and DNA damage with applications across many research fields including cancer research, photobiology, dermatology, ophthalmology, immunology, and cosmetics science.

To better study molecular events surrounding UV-induced DNA damage and repair, Mori et al. previously developed and characterized monoclonal antibody (mAb) specific for CPDs and mAb specific for 6-4PPs (1) while Matsunaga et al. developed and characterized mAb specific for DewarPPs (2). Three of these antibodies (CPDs: clone TDM-2; 6-4PPs: clone 64M-2; DewarPPs: clone DEM-1) continue to be cited frequently in the literature, often for use in ELISA by a recommended procedure.

Read more about High Sensitivity CPD/ Cyclobutane Pyrimidine Dimer ELISA kit and High Sensitivity 6-4PP/ (6-4)Photoproducts ELISA kit.





Product List
Description Cat. No. Size List Price Discount Campaign Price
High Sensitivity 6-4PP/ (6-4) photoproduct ELISA kit CSR-NM-MA-K002 1 KIT (96 TESTS) ¥100,000 20% ¥80,000
High Sensitivity 6-4PP/ (6-4) photoproduct ELISA kit Ver.2 CSR-NM-MA-K004 1 KIT (96 TESTS) ¥100,000 20% ¥80,000
High Sensitivity CPD ELISA kit Ver.2 CSR-NM-MA-K003 1 KIT (96 TESTS) ¥100,000 20% ¥80,000
PROTAMINE SULFATE COATED ELISA PLATE 96 x 5 CSR-NM-MA-P002 1*5 PLATE ¥9,500 20% ¥7,600
PROTAMINE SULFATE COATED ELISA PLATE 96 x 10 CSR-NM-MA-P003 1*10 PLATE ¥18,000 20% ¥14,400
UVC-irradiated DNA samples CSR-NM-MA-R010 5*10 UG ¥30,000 20% ¥24,000